Though men tend to smoke greater amounts and more frequently than women, women tend be more sensitive to marijuana consumption.
We know women and men react differently to cannabis. The endocannabinoid system — the set of receptors that bond with consumed marijuana — interacts directly and indirectly with estrogen in a women’s body. A 2009 study, published in the European Journal of Pharmacology, found the amount of CB1 receptors in a woman’s body fluctuates depending on estrogen levels, meaning women experience more intense highs when their estrogen levels peak.
Though men tend to smoke greater amounts and more frequently than women, a 2014 study from Washington State University found that women tend be more sensitive to marijuana consumption. Another difference: men are more likely to get the munchies.
Published in the Journal of Addiction Medicine, scientists from the University of Texas-Dallas found that when it comes to regular marijuana consumers, women experience more intense craving than men. In addition, when women self-reported higher estrogen levels due to their menstrual cycles, they rated their marijuana cravings higher on average.
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