While conceding there is “reasonable evidence” that cannabis can help with nausea and vomiting after chemotherapy and may improve spasticity in conditions like multiple sclerosis, there is little to suggest cannabinoids help with pain, and “if they do, it is neuropathic pain and the benefit is likely small.
Medical Xpress reports…
“Medical cannabinoids have been advocated for an extensive variety of conditions, from glaucoma to cancer,” wrote Allan. “Unfortunately, bias is pervasive throughout the medical cannabinoid literature, including in randomized controlled trials.
“This is compounded by poor reporting in the media, with 79 per cent of medical cannabinoid newspaper stories providing inappropriate information, most of which was sensationalism.”
However, some researchers say the anecdotal promise of medical cannabis is too strong to ignore, and are poised to go after supporting evidence. Some of that clinical proof is already starting to emerge as more researchers take up the quest.
As yet, there are no known side-effects or indications of dependence.
Earlier this year, the U.S. Food and Drug Administration approved the CBD-based drug Epidiolex, used to treat severe epilepsy, especially Lennox-Gastaut syndrome and Dravet syndrome, two of the most debilitating forms of the disease in children.
More to it than CBD
U of A pharmacy researcher Raimar Loebenberg said he is eager to contribute to the nascent body of clinical data. He has started exploring the analgesic properties of CBD topical creams to see whether the hype is justified.
Producers of the cream claim it relieves muscle soreness. Some reports even suggest it can be effective in combatting skin cancer, said Loebenberg.
One big problem with unregulated CBD products, he said, is unreliable quality and inconsistent dosing. Some producers may also fail to recognize the pharmaceutical complexity of the marijuana plant, and the way in which its cannabinoids interact with the endocannabinoid receptors in our bodies.
It could prove that isolating any one cannabinoid for medical purposes is in some cases self-defeating.